Cerebellar Kv2.1 Downregulation, Cytoarchitectural Alterations, and Persistent Motor Impairments Following Subchronic Phencyclidine Exposure.
Neuropharmacology June 1, 2026 L. Lagojda, Leah MacGregor, Mahfuza Maisha et al.
Dysfunction of the cerebellum is increasingly recognised as a contributor to schizophrenia. As one of the most ubiquitous voltage-gated potassium channels in the brain, the expression and function of Kv2.1 remains underexplored in the cerebellum, and its potential involvement in cerebellar pathophysiology in schizophrenia is unknown. Here, we characterised the expression pattern of Kv2.1 in the...