Esketamine for negative emotions and cognitive function in general anesthesia: a systematic review and meta-analysis
Frontiers in Medicine June 12, 2026 Xiaofan Yang, Jing Qin, Wenqing Xu
Introduction This study aims to systematically evaluate, through a systematic review and meta-analysis, the effect of esketamine on postoperative negative emotions (anxiety and depression) and cognitive function in patients undergoing general anesthesia. Methods Following PRISMA guidelines, we systematically searched PubMed, Web of Science, Embase, Cochrane Library, and CNKI to identify studies...