286. Restoration by ketamine metabolites of cognitive and affective prosocial behaviors in a mouse model of depression
International Journal of Neuropsychopharmacology September 9, 2026 R Yokoyama, M Matsumi, S Asano et al.
Abstract Background The execution of prosocial behaviors requires the ability to accurately understand and infer others’ affective states. Impairments in prosocial functioning have been shown to be associated with the pathology of several psychiatric disorders. In particular, individuals with depression exhibit reduced cognitive and affective responses to others’ emotions. These impairments may...