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K Brennan

1 paper in the library · publishing 2026

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828. Psilocin attenuates polyinosinic:polycytidylic acid (Poly I:C)-indued interferon responses in human peripheral blood mononuclear cells

The International Journal of Neuropsychopharmacology September 1, 2026 C Sheridan, G Thuery, K Brennan et al.

Abstract Background Serotonergic psychedelics have recently re-emerged as promising therapeutic agents in psychiatry, showing positive outcomes in clinical trials for treatment-resistant depression, major depression, and PTSD. However, their effects on the immune system are poorly characterized. It remains unclear whether these compounds exert immunomodulatory effects that contribute to their...