Cannabinoid receptor localization in brain.
Proceedings of the National Academy of Sciences of the United States of America March 1990 M Herkenham, A B Lynn, M D Little et al.
[3H]CP 55,940, a radiolabeled synthetic cannabinoid, which is 10-100 times more potent in vivo than delta 9-tetrahydrocannabinol, was used to characterize and localize a specific cannabinoid receptor in brain sections. The potencies of a series of natural and synthetic cannabinoids as competitors of [3H]CP 55,940 binding correlated closely with their relative potencies in several biological...