Plasma leptin levels are lower in females, but not males, with ketamine use disorder.
The American Journal of Drug and Alcohol Abuse September 2, 2024 Ming-Chyi Huang, Li-Jung Chiang, Wan-Hsi Chien et al.
Background: Ketamine has emerged as a prominent substance of misuse. Leptin, an adipocyte-derived polypeptide hormone, has been implicated in the development of addiction. Sex-specific changes in leptin levels have been demonstrated following acute ketamine administration; the persistence of long-term ketamine use on leptin levels is uncertain.Objectives: To assess the sex-difference of leptin...