Studies of dioxole ring substituted 3,4-methylenedioxyamphetamine (MDA) analogues.
Pharmacology, biochemistry, and behavior November 1989 D E Nichols, R Oberlender, K Burris et al.
The 3,4-ethylidenedioxy and 3,4-isopropylidenedioxy analogues, EDA and IDA, respectively, of 3, 4-methylenedioxyamphetamine (MDA) were compared to MDA in drug-stimulated [3H]-serotonin overflow from prelabelled rat hippocampal slices, [3H]-dopamine overflow from prelabelled rat caudate slices, in their ability to displace the 5-HT2 agonist R-[125I]-DOI from rat brain cortical binding sites....