The influence of ketamine on regional brain glucose use.
Anesthesiology August 1988 D W Davis, A M Mans, J F Biebuyck et al.
The purpose of this study was to determine the effect of different doses of ketamine on cerebral function at the level of individual brain structures as reflected by glucose use. Rats received either 5 or 30 mg/kg ketamine intravenously as a loading dose, followed by an infusion to maintain a steady-state level of the drug. An additional group received 30 mg/kg as a single injection only, and...