Behavioural and neuroendocrine responses to D-fenfluramine in rats treated with neurotoxic amphetamines
Journal of Psychopharmacology May 1, 1995 Hugh Series, Marisa Le Masurier, Sarah E. Gartside et al. 13 citations
The amphetamine derivatives p-chloroamphetamine (pCA), 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy') and D-fenfluramine can, if given repeatedly in high doses to rats, produce a degeneration of serotonergic nerve terminals which we have previously shown to result in a reduction in D-fenfluramine-evoked release of 5-HT in vivo. It is therefore possible that fenfluramine-evoked responses...