LSD-25 in doses of 130 to 1300 µg/kg induced a small and significant rise in levels of rat brain serotonin within 10 to 120 minutes following administration. A single dose was as effective as several daily doses. In reserpine treated animals, LSD-25 induced a 2-fold elevation in brain serotonin, and effects were found 96 hours following a single dose of LSD-25. A dose-effect interaction of...
RAUWOLFIA. By R. E. Woodson, Jr., H. W. Youngken, E. Schlittler, and J. A. Schneider. Boston, Toronto, Little, Brown and Co., 1957. 137 pp. $5.50. For research workers who are interested in this important group of alkaloids, which includes the fascinating drug reserpine, this should prove to be a useful and compact reference volume because it is an attempt to collate all pertinent information...