Characterization of 17 unknown ketamine manufacturing by-product impurities by UHPLC-QTOF-MS.
Drug Testing and Analysis August 1, 2024 Cui-Mei Liu, Zhen-Dong Hua, Wei Jia et al. 7 citations
This study initially reported the selection and characterization of 17 unknown impurities attributed to the manufacture process of ketamine. A total of 150 seized ketamine samples were investigated through ultra-high-performance liquid chromatography-quadrupole-time of flight (UHPLC-Q-TOF). Seventeen characteristic impurities were selected in accordance with four criteria: The compound was...