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Robert G Shulman

1 paper in the library · publishing 2009

Papers

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Baseline brain energy supports the state of consciousness.

Proceedings of the National Academy of Sciences of the United States of America July 7, 2009 Robert G Shulman, Fahmeed Hyder, Douglas L Rothman

An individual, human or animal, is defined to be in a conscious state empirically by the behavioral ability to respond meaningfully to stimuli, whereas the loss of consciousness is defined by unresponsiveness. PET measurements of glucose or oxygen consumption show a widespread approximately 45% reduction in cerebral energy consumption with anesthesia-induced loss of consciousness. Because...