Boris B Gorzalka

2 papers in the library · publishing 2004-2014

Papers

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Sex, drugs, and adult neurogenesis: sex-dependent effects of escalating adolescent cannabinoid exposure on adult hippocampal neurogenesis, stress reactivity, and amphetamine sensitization.

Hippocampus March 2014 Tiffany T-Y Lee, Steven R Wainwright, Matthew N Hill et al.

Cannabinoid exposure during adolescence has adverse effects on neuroplasticity, emotional behavior, cognition, and reward sensitivity in adult rats. We investigated whether escalating doses of the cannabinoid receptor 1 (CB1 R) agonist, HU-210, in adolescence would affect adult hippocampal neurogenesis and behavioral processes putatively modulated by hippocampal neurogenesis, in adult male and...

DOI: 10.1002/hipo.22221 Full text Cb1 receptor Hpa axis Periadolescent Sex difference +1

Prolonged cannabinoid treatment results in spatial working memory deficits and impaired long-term potentiation in the CA1 region of the hippocampus in vivo.

European Journal of Neuroscience August 2004 Matthew N Hill, David J Froc, Christopher J Fox et al.

Adult male Long-Evans rats were administered the potent cannabinoid 1 receptor agonist HU-210 (100 microg/kg, i.p.) for 15 days continuously and their performance on a matching-to-place version of the Morris water maze was subsequently evaluated. Overall, experimental animals performed significantly worse initially on the reference memory component of this task, but their performance improved...

DOI: 10.1111/j.1460-9568.2004.03522.x Full text