Gabriel Berenbeim

Chronic Inflammatory Pain Alters Expression of Limbic MAPK Phosphatases.

Chronic pain & management 2024 Dakota Nerland, Allison Ash, Adam Garman et al. 1 citation

Brain mechanisms involved in comorbidity between chronic pain conditions and clinical depression are still largely unknown. Our previous studies demonstrated that expression of mitogen-activated protein kinase phosphatase-1 (MKP-1) is both necessary and sufficient for the development of enhanced behavioral emotionality (i.e., depressive- like behaviors) in rodents. Here, we investigated the...