NMDA receptor antagonists augment antidepressant-like effects of lithium in the mouse forced swimming test.
Journal of psychopharmacology (Oxford, England) April 2010 M Ghasemi, M Raza, A R Dehpour
Although there is evidence of the involvement of N-methyl-D-aspartate receptors (NMDAR) in the action of lithium, its role in the antidepressant effects of lithium in a behavioural model remains unclear. In this study, we evaluated the effects of NMDAR antagonists on the antidepressant-like effects of lithium in the mouse forced swimming test. Lithium (30 and 100 mg/kg, i.p.) significantly (P <...