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Yuki Sasaki

2 papers in the library · publishing 2023-2025

Papers

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Effects of 3,4-methylenedioxymethamphetamine on neural activity in the nucleus accumbens of male mice engaged in social behavior.

Neuropsychopharmacology Reports March 1, 2025 Naoya Nishitani, Yuki Sasaki, Katsuyuki Kaneda

3,4-methylenedioxymethamphetamine (MDMA), a commonly abused recreational drug, induces prosocial effects such as increased sociability and empathy. The nucleus accumbens (NAc) has been suggested to play a crucial role in these MDMA-mediated prosocial effects. However, the relationship between social behavior and NAc neural activity, and the effects of MDMA on this relationship, remain unknown....

DOI: 10.1002/npr2.12510 (opens in new tab) Full text (opens in new tab) 3,4‐methylenedioxymethamphetamine Calcium imaging Fiber photometry Nucleus accumbens +4

Role of 5-HT1A receptors in the basolateral amygdala on 3,4-methylenedioxymethamphetamine-induced prosocial effects in mice.

European Journal of Pharmacology March 10, 2023 Hirohito Esaki, Yuki Sasaki, Naoya Nishitani et al.

3,4-methylenedioxymethamphetamine (MDMA), a recreational drug, induces euphoric sensations and psychosocial effects, such as increased sociability and empathy. Serotonin, also called 5-hydroxytryptamine (5-HT), is a neurotransmitter that has been associated with MDMA-induced prosocial effects. However, the detailed neural mechanisms remain elusive. In the present study, we investigated whether...

DOI: 10.1016/j.ejphar.2023.175653 (opens in new tab) MDMA Animals Mice, inbred icr N-methyl-3,4-methylenedioxyamphetamine +8