How small is a microdose, how big is a macrodose? Clarifying the lexicon of psychedelic research and treatment
Drug Science Policy and Law August 1, 2026 V. Polito
Nutt et al. recently proposed a common lexicon for psychedelic science including dosing categories for different forms of psychedelic use across multiple substances. Although common dosing terminology is an important advance, this paper identifies four challenges with Nutt et al.'s proposed categories. First, microdosing was defined as subperceptual; however, in both scientific and naturalistic...