Beyond head-twitch response: Acute psilocybin affects spontaneous behaviors in rats in a dose-dependent manner.
Journal of psychopharmacology (Oxford, England) August 25, 2026 Praachi Tiwari, Bryan W Jenkins, Catherine F Moore et al.
Psychedelics have emerged as promising pharmacological agents for treating a range of neuropsychiatric disorders. While preclinical studies have provided valuable insight into the neural mechanisms underlying their effects, systematic characterization of psychedelic effects on inherent spontaneous behaviors in animal models remains limited. In the current study, male and female Sprague-Dawley...