Integrative Use of Esketamine and Psychotherapy in a Real-World Outpatient Setting: A Mixed-Methods Case Series
European Psychiatry June 1, 2026 N. Ayad, S. Makhoul, F. Alkhaja
Introduction Treatment-resistant depression remains a major clinical challenge, with many patients experiencing relapse despite advances in medication and psychotherapy. Esketamine offers rapid relief from depressive symptoms, while psychotherapy helps patients build lasting skills to manage their condition. Despite their individual effectiveness, little is known about how these treatments work...