Psilocybin as serotonergic therapy in epilepsy: Narrative review of potentials and limitations.
British Journal of Clinical Pharmacology July 21, 2026 M. B. Cervera-Sánchez, Daniel San-Juan, Roberto Díaz-peregrino et al.
Psilocybin shows potential in neuropsychiatric disorders but has a complex relationship with epilepsy and seizures. We reviewed literature up to November 2025 to identify studies relevant to psilocybin's effects on seizures and epilepsy, including our research on serotonergic modulation. Core studies addressing the research question and supplementary mechanistic evidence were included for...