An integrative model of ketamine-induced memory dysfunction: From synapse to circuit in clinical context.
Neurotoxicology August 30, 2026 Mola Mohammadi, Amin Saeedi, Ali Asghar Kheirkhah Vakilabad et al.
Ketamine presents a modern pharmacological paradox, acting as both a rapid-acting antidepressant and a drug of abuse with significant cognitive consequences. While its therapeutic potential is revolutionary, chronic exposure is increasingly associated with persistent and specific deficits in episodic and working memory. This narrative review moves beyond descriptive lists of ketamine's effects...