Intranasal esketamine for ECT-refractory bipolar depression: a case report
Frontiers in Psychiatry July 30, 2026 Muhammad Abbas, Bruno Kallas, Max Garris
This is a case report of a 52 year old female with ECT-refractory bipolar depression who was treated with esketamine nasal spray, leading to a noticeable improvement in her depressive symptoms. She experienced a relapse after a reduction in her maintenance treatment in conjunction with psychosocial stressors, but improved once again after returning to her induction regimen. She tolerated the...