Psilocibina e neuroplasticidade: novas perspectivas terapêuticas para depressão resistente
Vértices September 1, 2026 Leticia Almeida Castro, André Luiz Anjos Simões Júnior, Guilherme Gianizeli Corradi Simões et al.
Depression is a multifactorial mental disorder and a leading cause of global disability. A subset of patients does not respond to conventional antidepressants, characterizing treatment-resistant depression (TRD). This study aimed to investigate the therapeutic potential of psilocybin in TRD, focusing on its effects on neuroplasticity. An integrative literature review was conducted using PubMed,...