MDMA as an early post-trauma intervention in a translational animal model of PTSD.
Progress in neuro-psychopharmacology & biological psychiatry July 24, 2026 Omer Baruch, Nadav Reiss, Doron Todder et al.
Post-traumatic stress disorder (PTSD) remains difficult to prevent after trauma, highlighting the need for early interventions that reduce the risk of chronic symptom development. This controlled study investigated the preventive potential of 3,4-methylenedioxymethamphetamine (MDMA) in a validated rat model of PTSD induced by predator scent stress (PSS). Adult male Sprague-Dawley rats (N = 175)...