The Strangest Drug Ever Studied: The Chemical Structure, History, and Enduring, Conjecturing Mystery of DMT
Zenodo (CERN European Organization for Nuclear Research) August 23, 2026 Benjamin Pham
This paper examines dimethyltryptamine (DMT) as one of the most unusual and scientifically provocative psychoactive substances ever studied. It traces DMT’s history from Indigenous Amazonian ayahuasca traditions and Richard Spruce’s nineteenth-century observations to twentieth-century psychedelic science, countercultural fascination, prohibition, and the modern revival of clinical research. The...