Longitudinal changes in depressive symptoms following naturalistic ayahuasca use: A prospective cohort study in Las Vegas, Nevada
medRxiv August 27, 2026 Krista Whitley, Kai Davide Castellarin, Kumar Dave et al. preprint
Abstract Ayahuasca use has expanded beyond its traditional Amazonian contexts, yet prospective longitudinal data examining depressive symptoms following naturalistic use in the United States remain limited. We conducted an interim analysis of an ongoing prospective observational cohort of adults participating in naturalistic ayahuasca use in Las Vegas, Nevada. Depressive symptoms were assessed...