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Crystal Weber

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Mapping excitatory synaptic plasticity evoked by single-dose psilocybin in mice

Ziming Li, Crystal Weber, Francesca Sellitti et al.

Abstract A single dose of psilocybin can induce long-lasting antidepressant effects. The neurobiological mechanisms underlying such sustained antidepressant effect remain insufficiently understood, particularly at the level of synaptic function and drug-target specificity. Here, we aimed to delineate single-dose psilocybin-induced excitatory synaptic plasticity. Synaptic plasticity was assessed...