Enantioselective determination of 3,4‐methylene‐dioxymethamphetamine and two of its metabolites in human urine by cyclodextrin‐modified capillary zone electrophoresis
Electrophoresis 1997 Matthias Lanz, Rudolf Brenneisen, Wolfgang Thormann 70 citations
Abstract Using capillary zone electrophoresis with a phosphate buffer at pH 2.5 containing 30 m M (2‐hydroxypropyl)‐β‐cyclodextrin as chiral selector, the simultaneous separation of the enantiomers of 3,4‐methylenedioxymethamphetamine (MDMA or Ecstasy) and its two metabolites 4‐hydroxy‐3‐methoxymethamphetamine (HMMA) and 3,4‐methylenedioxyamphetamine (MDA) in human urine is reported. The assay...