Background: Depression is a multifactorial disorder involving neurotransmitter dysregulation, HPA axis hyperactivity, neuroinflammation, and impaired neuroplasticity. While combination psychotherapy and pharmacotherapy remains first-line, ~30% of patients develop TRD. In the last few years ketamine has emerged as a rapid-acting therapeutic option for treatment-resistant cases. Aim: To review...
Background: Schizophrenia is a complex mental disorder influenced by both genetic and environmental factors. Cannabis use, particularly products with high tetrahydrocannabinol (THC) content, has been identified as a potential environmental risk factor for psychosis. Aim: This review aims to summarize current knowledge on the epidemiology, etiopathogenesis, and risk factors of schizophrenia,...