Myelin Repair as a Novel Mechanism for Ketamine's Sustained Antidepressant Effects.
Current Neuropharmacology January 16, 2025 Sen Wang, Chaoli Huang, Mengyu Wang et al. 4 citations
Depression is a prevalent mental disorder, affecting approximately 300 million people worldwide. Despite decades of research into the underlying mechanisms of depression, a consensus remains elusive. Recent studies have implicated changes in oligodendrocytes and myelin in the pathogenesis of depression. Conventional antidepressants may alleviate symptoms within weeks of use, but approximately...