Brain acid sphingomyelinase controls addiction-related behaviours in a sex-specific way.
Neurobiology of Disease March 1, 2025 Liubov S. Kalinichenko, Iulia Zoicas, Anne-Marie Bienia et al. 4 citations
Addiction is a chronic and severe mental disorder with high gender- and sex-specificity. However, the pathogenesis of this disorder is not fully elucidated, and no targeted pharmacotherapy is available. A growing body of evidence points out the potential involvement of the ceramide system in the pathophysiology of addiction. A pathogenic pathway for several mental disorders based on the...