Nitrous Oxide Abuse-Induced Vitamin B12 Deficiency and Neurological Injury
IntechOpen eBooks May 28, 2026 Li Wang (15202), Sedine Marie Desiree Nina Agbo, Jin Zhang et al.
Nitrous oxide (NO), often recognized as “laughing gas” in medicine, has seen a surge in recreational use among young people over the last decades. While its medical application is generally safe at controlled doses, its abuse has raised major concerns due to its potential toxicity. The most commonly reported sequelae are associated with subacute combined degeneration of the spinal cord, and...