Exposure to the Psychedelic Substance 25H-NBOMe Disrupts Maternal Care in Lactating Rats and Subsequently Impairs the Social Play Behavior of the Offspring.
Behavioural Brain Research February 1, 2024 Larissa M.a. Melo, Wellington A De Barros, Ângelo de Fátima et al.
Given the critical role of maternal care in the neurodevelopment of offspring, this study aimed to investigate the effects of the psychedelic substance 25H-NBOMe on maternal behavior in lactating rats and its subsequent impact on the social and neurodevelopmental behavior of the offspring. We administered two different dosages of 25H-NBOMe (0.3mg/kg and 1.0mg/kg; i,p,) to lactating rats and...