Reduced auditory evoked gamma-band response and schizophrenia-like clinical symptoms under subanesthetic ketamine
Neuropsychopharmacology February 6, 2019 Stjepan Curic, Gregor Leicht, S. Thiebes et al.
Abnormal gamma-band oscillations (GBO) have been frequently associated with the pathophysiology of schizophrenia. GBO are modulated by glutamate, a neurotransmitter, which is continuously discussed to shape the complex symptom spectrum in schizophrenia. The current study examined the effects of ketamine, a glutamate N-methyl-d-aspartate receptor (NMDAR) antagonist, on the auditory-evoked...