Investigación sobre microdosificación con hongos psilocibios: un artículo de reflexión
Cultura y Droga October 19, 2023 Laura Duque
This reflection article on microdosing with psilocybin is based on observational studies, clinical trials, a systematic review, and a sociological study. The evidence for positive effects comes mainly from anecdotal reports, but these results are difficult to replicate in controlled studies. The systematic review did not specify results related to psilocybin but found a general improvement in mental health; results for anxiety and stress were mixed, while positive outcomes were found for creativity and well-being. The difficulty of isolating the influence of expectations and placebo is noted. Laboratory studies have very small samples to be significant. The current state of research on microdosing with psilocybin can inform future research scenarios in both preclinical and clinical phases, with attention to confounding factors, qualitative aspects, and the practice itself.