Molecular and Cellular Mechanisms of Rapid-Acting Antidepressants Ketamine and Scopolamine
Current Neuropharmacology March 10, 2016 Eric S. Wohleb, Danielle M. Gerhard, Alex Thomas et al. 148 citations
Major depressive disorder (MDD) is a prevalent neuropsychiatric disease that causes profound social and economic burdens. The impact of MDD is compounded by the limited therapeutic efficacy and delay of weeks to months of currently available medications. These issues highlight the need for more efficacious and faster-acting treatments to alleviate the burdens of MDD. Recent breakthroughs...