Towards an expanded neurocognitive account of ketamine's rapid antidepressant effects.
The International Journal of Neuropsychopharmacology February 4, 2025 Yingliang Dai, Ben J. Harrison, Christopher G. Davey et al. 6 citations
Ketamine is an N-methyl-D-aspartate receptor antagonist that has shown effectiveness as a rapidly acting treatment for depression. Although advances have been made in understanding ketamine's antidepressant pharmacological and molecular mechanisms of action, the large-scale neurocognitive mechanisms driving its therapeutic effects are less clearly understood. To help provide such a framework,...
DOI: 10.1093/ijnp/pyaf010 (opens in new tab)
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Neurocognitive
Depression/mental-health/mood-disorders
Ketamine/psychopharmacology/antidepressants
Neuroscience/neurobiology/brain-research