Nuria Sánchez-Fernández

Long-lasting behavioral, molecular and functional connectivity alterations after chronic THC exposure during adolescence in mice.

Progress in Neuro-Psychopharmacology and Biological Psychiatry July 13, 2025 Laura Gómez-Acero, Federico Varriano, Nuria Sánchez-Fernández et al.

Heavy and daily use of cannabis with high contents of Δ9-tetrahydrocannabinol (THC) during adolescence is associated with an increased risk of developing psychotic disorders later in life. Here, we treated mice with THC during adolescence and found that this exposure impaired social interaction and increased vulnerability to develop sensorimotor gating deficiencies comparable to those...