Hallucinogens, serotonin and obsessive-compulsive disorder.
Journal of Psychoactive Drugs 1998 P L Delgado, F A Moreno
The serotonin (5-HT) neurotransmitter system has been implicated in the pathophysiology of several neuropsychiatric disorders, especially obsessive-compulsive disorder (OCD). Blockade of 5-HT reuptake appears to be an important initial neurobiological event in the therapeutic mechanism of action of antiobsessional drugs. However, for reasons that continue to be poorly understood, clinical...