Esketamine ameliorates prenatal stress-induced postpartum depression and sex-related behavioral differences in adolescent progeny.
Neuropharmacology May 15, 2025 Yazhou Wen, Jin Zhou, Huiling Yu et al. 2 citations
Prenatal stress leads to postpartum depression and is associated with developmental issues in offspring. Esketamine quickly and effectively prevents or treats postpartum depression. However, the long-term effects of esketamine on progeny development are unknown. CRS during pregnancy was used to establish the postpartum depression animal model. After confirming pregnancy, all mice were randomly...