Esketamine ameliorates prenatal stress-induced postpartum depression and sex-related behavioral differences in adolescent progeny.
Neuropharmacology May 15, 2025 Yazhou Wen, Jin Zhou, Huiling Yu et al. 2 citations
Prenatal stress leads to postpartum depression and is associated with developmental issues in offspring. Esketamine quickly and effectively prevents or treats postpartum depression. However, the long-term effects of esketamine on progeny development are unknown. CRS during pregnancy was used to establish the postpartum depression animal model. After confirming pregnancy, all mice were randomly...
DOI: 10.1016/j.neuropharm.2025.110354 (opens in new tab)
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Chronic restraint stress
Postpartum depression ppd
Postnatal depression
Psychiatric care
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