Brain-derived neurotrophic factor (BDNF) changes in rodent models of schizophrenia induced by ketamine: a systematic review.
Naunyn-Schmiedeberg's archives of pharmacology February 20, 2025 Atefeh Motamedi-Manesh, Mahdieh Farzin Asanjan, Hamed Fallah et al. 6 citations
Schizophrenia is a severe neuropsychiatric disorder ranking among the top ten global disability causes. In rodents, sub-chronic or chronic ketamine treatment is used for the induction of schizophrenia. Ketamine affects the function of brain-derived neurotrophic factor (BDNF), the most important neurotrophin involved in the pathophysiology of different neuropsychiatric disorders. The present...