Sleep/wake changes in perturbational complexity in rats and mice.
iScience March 17, 2023 Matias Lorenzo Cavelli, Rong Mao, Graham Findlay et al.
In humans, the level of consciousness is assessed by quantifying the spatiotemporal complexity of cortical responses using Perturbational Complexity Index (PCI) and related PCIst (st, state transitions). Here we validate PCIst in freely moving rats and mice by showing that it is lower in NREM sleep and slow wave anesthesia than in wake or REM sleep, as in humans. We then show that (1) low PCIst...