Investigation of Psychiatric and Neuropsychological Correlates of Default Mode Network and Dorsal Attention Network Anticorrelation in Children.
Cerebral Cortex December 18, 2019 M. Owens, D. Yuan, S. Hahn et al. preprint
The default mode network (DMN) and dorsal attention network (DAN) typically show an 'anticorrelation' in healthy adults, reflecting a separation between internal and external thought. Reduced separation of these networks has been proposed as a mechanism for cognitive deficits in psychiatric disorders, but this link had rarely been tested in pre-adolescent children. Using data from the Adolescent Brain Cognitive Development study, the largest sample to date of 9- to 10-year-old children (N=6543), the analysis examined the relationship between DMN/DAN anticorrelation strength and psychiatric symptoms.