Dissociations between glucose metabolism and blood oxygenation in the human default mode network revealed by simultaneous PET-fMRI
Proceedings of the National Academy of Sciences of the United States of America June 30, 2021 L. Stiernman, F. Grill, A. Hahn et al.
Significance A consistent finding from functional MRI (fMRI) of externally focused cognitive control is negative signal change in the brain’s default mode network (DMN), but it is unknown whether this reflects an increase of synaptic activity during rest periods or active suppression during task. Using hybrid PET-MRI, we show that task-positive fMRI responses align with increasing glucose...