Effective Connectivity for Default Mode Network Analysis of Alcoholism
Brain Connectivity February 1, 2021 Danish M. Khan, Nidal Kamel, Mustapha Muzaimi et al.
Electroencephalography (EEG), with its high temporal resolution, was used to estimate effective connectivity within the default mode network (DMN) in 20 subjects with alcoholism and 25 healthy controls. The resulting connectivity diagrams revealed unidirectional causal effects among DMN regions. Variations in these causal effects between controls and alcoholics correlated with symptoms commonly associated with alcoholism, such as cognitive and memory impairments, executive control deficits, and attention deficiency. The findings provide insight into how alcohol modulates cognitive and executive functions, potentially aiding treatment for alcohol use disorder.