The immunomodulatory effects of psychedelics in Alzheimer's disease-related dementia.
Neuroscience January 9, 2025 Alireza Mohammad Hosseini, Hossein Khaleghzadeh-Ahangar, Atena Rahimi
Dementia is an increasing disorder, and Alzheimer's disease (AD) is the cause of 60% of all dementia cases. Despite all efforts, there is no cure for stopping dementia progression. Recent studies reported potential effects of psychedelics on neuroinflammation during AD. Psychedelics by 5HT2AR activation can reduce proinflammatory cytokine levels (TNF-α, IL-6) and inhibit neuroinflammation. In...