Cooperation and competition between the default mode network and frontal parietal network in the elderly
Frontiers in Psychology May 19, 2023 Hideya Koshino, Mariko Osaka, Tetsuya Shimokawa et al.
Older adults show altered brain network dynamics during working memory tasks. The Default Mode Network (DMN) typically deactivates during task execution and coactivates with the Frontal Parietal Network (FPN) during task preparation. Compared to younger adults, older adults exhibited reduced DMN activity during preparation and reduced DMN deactivation during execution, but higher FPN activation during execution. Functional connectivity was weaker within the DMN and FPN, and between these networks, in older adults. These connectivity reductions may underlie age-related cognitive decline.