Dynamic Adaptation of Default Mode Network in Resting state and Autobiographical Episodic Memory Retrieval State
Garam Jeong, Marco Paolini preprint
The default mode network processes mental states involving internal representations of subjective experiences, such as autobiographical memory retrieval and resting states. A novel analysis method called one-to-many dynamic functional connectivity analysis for fMRI was developed to detect how a single brain network's dynamics adapt depending on the mental state. Applied to a single late-blind subject with advanced mental imagery ability, the method examined the default mode network during three autobiographical memory retrieval states and a resting state. The posterior cingulate cortex as the center best depicted dynamic adaptation between mental states. The correlation between the posterior cingulate cortex and the right parahippocampal cortex varied most, contributing relatively more to dynamic adaptation.