Source-level α periodic power in visual and default mode networks predicts topiramate treatment response in migraine
The Journal of Headache and Pain July 17, 2026 Siyuan Xie, Chenghui Pi, Kang Jin et al.
BACKGROUND: Migraine is highly heterogeneous, and patients exhibit substantial variability in their responses to preventive treatment. The dose-escalation strategy of topiramate further complicates early evaluation of therapeutic efficacy. Identifying neurobiological markers that can predict treatment response is therefore essential for individualized therapy. In this study, we constructed...