Influence of mindfulness meditation on intracranial EEG parameters in epileptic and non-epileptic brain areas.
Epilepsy & behavior : E&B December 1, 2024 Daniel D Cummins, Zac Schulman, Christina Maher et al.
During mindfulness meditation compared with mind-wandering, gamma power (30-55 Hz) in the mesial temporal lobe (MTL) significantly decreased in non-epileptic brain tissue but not in epileptic tissue. No significant power changes occurred in epileptic MTL across any frequency band, but aperiodic components (offset, knee, exponent) differed significantly between the two states in epileptic MTL, while no such aperiodic changes appeared in non-epileptic MTL. These intracranial electrophysiological modulations suggest that gamma activity changes in non-epileptic MTL may reflect functional brain state shifts, whereas aperiodic changes in epileptic MTL may relate to seizure propensity.